Zhimu-Huangbo ameliorates AQP4 depolarization in diabetic cognitive impairment rats by targeting the serum-derived exosomal TIMP3-mediated MMP9/β-DG pathway

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Drug Discov Ther. 2025; 19(6):360-377.

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Real-world use of non-oral administration of oral anticancer agents via the simple suspension method in Japanese patients with cancer: A nationwide claims-based analysis

Ohta H, Yasu T

Drug Discov Ther. 2025; 19(6):378-388.

DOI: 10.5582/ddt.2025.01095

Disproportionality and time-to-onset analyses of drug-induced weight gain using the Japanese Adverse Drug Event Report database

Ide N, Shibata R, Sako KI and Maeda T

Drug Discov Ther. 2025; 19(6):389-394.

DOI: 10.5582/ddt.2025.01096

Verification of the protective effect of transfecting brain-derived neurotrophic factor and B-cell lymphoma 2 genes on retina ganglion cells in a rat model of optic nerve injury

Zhao ZJ, Fang Y, Xu GZ, Xiong JW, Mo XF, Fan JW

Drug Discov Ther. 2025; 19(6):395-403.

DOI: 10.5582/ddt.2025.01101

A phase II investigator-initiated, continuation trial of 5-aminolevulinic acid hydrochloride/sodium ferrous citrate (5-ALA-HCl/SFC) for patients with adult-onset Still's disease (AOSD) refractory to glucocorticoids

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Drug Discov Ther. 2025; 19(6):404-413.

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Comparative study of contrast-enhanced ultrasound and contrast-enhanced computed tomography in the diagnosis of benign and malignant lesions of the gallbladder

Fang L, Qiu ZY, Xu LW, Hu F, Tao YC, Ding SN, Zhou J, Wang L, Chen L

Drug Discov Ther. 2025; 19(6):414-424.

DOI: 10.5582/ddt.2025.01105

Modulatory effects of ingesting dietary fiber and protein before carbohydrates on postprandial interstitial glucose responses

Wada IY, Tanaka S, Watanabe C, Shimokawa K, Ishii F

Drug Discov Ther. 2025; 19(6):425-430.

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Clinical significance of imeglimin in older patients with type 2 diabetes: Analysis of a national database and a long-term case suggesting the potential for sarcopenia prevention

Ishimura A, Hashimoto K, Ogino H

Drug Discov Ther. 2025; 19(6):431-434.

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Elamipretide: The first cardiolipin-directed mitochondrial therapeutic for Barth syndrome approved under accelerated approval

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Drug Discov Ther. 2025; 19(6):435-436.

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New diagnostic code "5B72 Undernutrition in Adults" approved for inclusion in the 11th Revision of the International Classification of Diseases (ICD-11)

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Drug Discov Ther. 2025; 19(6):437-439.

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